Spatial and Behavioural
Plant-Microbe Interactions
at Cellular Resolution

I study how plant immune responses are organized at cell-type-specific resolution in the root, and how pathogenic bacteria manipulate the extracellular space to promote their colonization and virulence.

Charles Roussin-Léveillée
Charles Roussin-Léveillée, Ph.D. Postdoctoral Researcher

About Me

I am an EMBO & Swiss National Science Foundation (SNF) postdoctoral fellow in the laboratory of Pr. Niko Geldner at the Université de Lausanne (UNIL), Switzerland. My current research focuses on divergent evolution of cell type functions in plant immunity, as well as on plant-mediated modulation of the Arabidopsis root rhizosphere microbiome behavior (control of pathogenic traits).

I completed my Ph.D. at the Université de Sherbrooke (Canada) in the laboratory of Pr. Peter Moffett, where my thesis examined extracellular microenvironments in plant-microbe interactions. I was particularly interested in how pathogenic bacteria transform the apoplastic space into a water- and nutrient-rich oasis that promotes their growth and virulence — and how plant cells fight back.

Before my Ph.D., I had the chance to explore plant biology through internships at the Université de Sherbrooke, the University of Toronto, and the Max Planck Institute for Plant Breeding Research in Cologne, Germany.

I am a strong advocate for equity, diversity, and inclusion in science, serving as Jr. Director of IS-MPMI and co-chair of its EDI Committee (2020–2023). Outside the lab, I am a fervent hiker and lover of wonders nature has to offer, intense foodie and ceramist.

Education & Positions
  • Apr 2024–
    Present
    Postdoctoral Fellow Geldner Laboratory · Université de Lausanne, Switzerland
    EMBO Fellow (2024–2026) · SNF Fellow (2026–2028)
  • Sep 2019–
    Mar 2024
    Ph.D. in Molecular Cell Biology Moffett Laboratory · Université de Sherbrooke, Canada
    Thesis: Extracellular microenvironments in plant-microbe interactions
  • Jan 2018–
    Sep 2019
    M.Sc. in Molecular Cell Biology Moffett Laboratory · Université de Sherbrooke, Canada
  • 2014–2017
    B.Sc. in Molecular Cell Biology (Co-op) Université de Sherbrooke, Canada
  • 2017
    Research Intern Max-Planck Institute for Plant Breeding Research, Cologne (Pr. Schulze-Lefert)

Research

My research spans two phases, both centered on understanding how plants and microorganisms interact at the molecular and cellular level.

Postdoctoral Research Geldner Lab · UNIL · 2024–present
🔬

Cell-Type-Specific Effector-Triggered Immunity

I investigate how effector-triggered immunity (ETI) is organized across distinct cell types in a developing Arabidopsis plant, combining high-resolution confocal imaging, NLR receptor biology, and cell-type-specific expression of Avirulence and Resistance genes to map immune responses at cellular resolution.

🌱

Plant-Mediated Control of Rhizosphere Microbiome Behavior at the Root Interface

I explore how plant immune and physiological programs shape the spatial organization and behavior of microbial communities in the rhizosphere, focusing on the molecular signals exchanged at the root-microbiome interface.

Doctoral Research Moffett Lab · Université de Sherbrooke · 2018–2024
🦠

Investigation of Conserved Pathogenic Virulence Traits and Establishment of the Extracellular Niche

I studied how evolutionarily conserved bacterial effectors manipulate host abscisic acid signaling to transform the apoplastic space into a water- and nutrient-rich microenvironment, and how plants counteract this pathogenic niche establishment.

🧬

Understanding the Plant Immune System from a Functional and Physiological Standpoint

I investigated how pattern- and effector-triggered immunity function against the conserved and induced pathogenic virulence program known as water-soaking. We found that the main physiological function of immunity is to prevent water acquisition by microbial life in the apoplast.

Publications

* First author  |  ✉ Corresponding author  |  ǂ Mentored trainee  |  Full list on Google Scholar →

2026
Glycan recognition by a plant sentinel immune receptor
Jiménez-Sandoval P, Broyart C, Kentish O, Lee HK, Culjak K, Osswald U, Aitouguinane M, Tettamanti E, Schmidli M, Zhang L, Roussin-Léveillée C, et al., Santiago J
Science – under review
2026
Sugarcane streak mosaic virus P1 protein targets the BES1 transcription factor to subvert DAMP-induced immunity in plant
He Z, Deng X, Xu X, Tang M, Hua Y, Qin L, Feng C, Gu T, Zhuang X, Xu K, Roussin-Léveillée C, Moffett P, Zhang K
Science Advances
2025
Co-occurrence of chloroplastic ROS production and salicylic acid induction in plant immunity
Roussin-Léveillée C*, St-Amand Mǂ, Desbiens-Fortin Pǂ, Perreault R, Pelletier A, Gauthier Sǂ, Gaudreault-Lafleurǂ, Laforest-Lapointe I, Moffett P
New Phytologist
2024
Extracellular niche establishment in plant-microorganism interactions
Roussin-Léveillée C*, Mackey D*, Gayani E, Reid G, Moffett P
Nature Reviews Microbiology
2024
The plant disease triangle facing climate change: a molecular perspective
Roussin-Léveillée C*, Rossi CAM, Castroverde DCM, Moffett P
Trends in Plant Science
2023
Light prevents pathogen-induced aqueous microenvironments via potentiation of salicylic acid signaling
Lajeunesse Gǂ*, Roussin-Léveillée C*✉, Boutin S, Fortin Éǂ, Laforest-Lapointe I, Moffett P
Nature Communications
2023
A jasmonic acid-related mechanism affects ARGONAUTE5 expression and antiviral defense against PVX in Arabidopsis thaliana
Silva-Martins G, Roussin-Léveillée C, Bolaji A, Pillay Veerapen V, Moffett P
Molecular Plant-Microbe Interactions (MPMI)
2023
Nematostoma parasiticum as causal agent of Herpotrichia needle browning of fir
Lerat S, Roussin-Léveillée C, Sidibé A, Moffett P, Beaulieu C
Plant Disease
2022
Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast
Roussin-Léveillée C*, Lajeunesse Gǂ, St-Amand Mǂ, Pillay Veerapen V, Silva-Martins G, Nomura K, Brassard Bǂ, Bolaji A, He SY, Moffett P
Cell Host & Microbe
2020
ARGONAUTE5 represses age-dependent induction of flowering through physical and functional interaction with miR156 in Arabidopsis
Roussin-Léveillée C*, Silva-Martins G*, Moffett P
Plant & Cell Physiology
2020
Natural variation in the Arabidopsis AGO2 gene is associated with susceptibility to Potato virus X
Brosseau C, Adurogbangba A, Roussin-Léveillée C, Zhao Z, Biga S, Moffett P
New Phytologist

Awards & Fellowships

Total fellowship & scholarship funding: > $800,000 CAD

Major Fellowships & Scholarships
  • Swiss National Science Funds Postdoctoral Fellowship · 2026–2028 · $376,000 CAD
  • EMBO Postdoctoral Fellowship · 2024–2026 · $300,000 CAD
  • FRQNT Doctoral Fellowship · 2022–2026 · $75,000 CAD
  • VoiceAge Doctoral Excellence Fellowship · 2020–2023 · $45,000 CAD · Université de Sherbrooke
  • FRQNT International Internship Scholarship · 2019 · $5,000 CAD
  • Excellence Scholarship, Quebec's Ministry of Higher Education · 2017 · $1,500 CAD
  • LOJIQ Scholarship for International Travel · 2017 · $1,000 CAD
  • Paul Desmarais Scholarship · 2017 · $1,500 CAD
Prizes & Awards
  • Best Thesis Award in Science or Engineering – Province of Quebec · ADESAQ, 2025
  • Best Thesis Award in Science or Engineering · Université de Sherbrooke, 2025
  • Louis-Berlinguet Rising Star Award · FRQNT, 2023
  • Ragai Ibrahim Award – Best Publication in Plant Sciences (Mention) · CSPB, 2023
  • Best Oral Presentation Award · CSPB Meeting, 2023
  • Louis-Berlinguet Rising Star Award · FRQNT, 2023
  • Gordon Research Conference Best Poster Award · 2022
  • Best Poster Award – Journées du Centre SEVE · 2021
  • Honorable Mention for Best Oral Presentation · 2021
  • ACFAS Best Oral Presentation · 2021

Contact

Open to discussions on plant immunity, collaborations, and opportunities.